Homo sapiens synaptic Ras GTPase activating protein 1 (SYNGAP1)
Synonyms:
MRD5; RASA1; RASA5; SYNGAP
Immunogen
Peptide with sequence DEDEIHPLLIRDR-C, from the N Terminus of the protein sequence according to NP_006763.2.
Buffer
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Clone Name
Isotype
Species Reactivity
Human, Mouse, Rat, Dog, porcine, Cow
Concentration
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. (Protein A or G Sepharose)
Guaranteed Application *
WB
Suggested Dilutions
WB: 1-3ug/ml
Background
The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5). [provided by RefSeq].
Related Pathway
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