Homo sapiens synaptic Ras GTPase activating protein 1 (SYNGAP1)
MRD5; RASA1; RASA5; SYNGAP
Peptide with sequence DEDEIHPLLIRDR-C, from the N Terminus of the protein sequence according to NP_006763.2.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Human, Mouse, Rat, Dog, porcine, Cow
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. (Protein A or G Sepharose)
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The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5). [provided by RefSeq].
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