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Home Antibody All anti-TPO antibodies

Anti-TPO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309510
  • Goat Polyclonal Antibody against thyroid peroxidase
100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenPeptide with sequence C-TRHVIQVSNEVVTDD, from the internal region of the protein sequence according to NP_000538.3; NP_783650.1; NP_783652.1; NP_783653.1.
Clone Name Isotype
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 0.3-1ug/ml
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Reference Data

Target NameHomo sapiens thyroid peroxidase (TPO), transcript variant 2
Alternative NameMSA; TDH2A; TPX
Database LinkNP_783650
FunctionThis gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq].
Related Pathway
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Jak-STAT signaling pathway

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WB Image
A309510 (0.3µg/ml) staining of Human Thyroid Gland lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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