Home Antibody All anti-NEFH antibodies
Also for NEFH (NM_012607)
|Purified bovine NF-H|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:50,000, IF: 1:25,000
|total IgY fraction in PBS + 10 mM NaN3.|
|Total IgY fraction
|Rattus norvegicus neurofilament, heavy polypeptide (Nefh)|
|Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq]. |
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Western blot of rat cortex lysate showing specific immunolableing of the ~200k NF-H protein.
Immunofluorescence of rat cortical neurons and glia showing NF-H staining (red).