Home Antibody All anti-UGT1A6 antibodies
Also for UGT1A6 (NM_205862)
|Recombinant fragment corresponding to a region within amino acids 8 and 227 of UGT1A6 (Uniprot ID#P19224)|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens UDP glucuronosyltransferase 1 family, polypeptide A6 (UGT1A6), transcript variant 2|
|GNT1; HLUGP; HLUGP1; UDPGT; UDPGT 1-6; UGT1; UGT1A6S; UGT1F|
Entrez Gene 54578 Human
|This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants. [provided by RefSeq]|
|Transmembrane Pentose and glucuronate interconversionsAscorbate and aldarate metabolismAndrogen and estrogen metabolismStarch and sucrose metabolismRetinol metabolismPorphyrin and chlorophyll metabolismMore Pathways >> |
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UGT1A6 antibody detects UGT1A6 protein by Western blot analysis. A. 50 ug mouse liver lysate/extract. 7.5 % SDS-PAGE. UGT1A6 antibody (TA309014) dilution: 1:500
Sample (30 ug of whole cell lysate). A: A431 . B: H1299. 7.5% SDS PAGE. TA309014 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded OV90 xenograft, using UGT1A6(TA309014) antibody at 1:100 dilution.