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Home Antibody All anti-REN antibodies

Anti-REN Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308950 Rabbit Polyclonal antibody to Renin (renin) 100ul $325 3-7 Days
LC424660 REN HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 70 and 332 of Renin (Uniprot ID#P00797)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Chimpanzee) Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 45kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Chimpanzee (100%)

Reference Data

Target NameHomo sapiens renin (REN)
Alternative NameHNFJ2
Database LinkNP_000528
Entrez Gene 5972 Human
FunctionRenin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq]
Related PathwaySecreted ProteinDruggable Genome Renin-angiotensin system

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Renin antibody [N2C2], Internal detects REN protein by Western blot analysis. A. 30 ug K562 whole cell lysate/extract. 10 % SDS-PAGE. Renin antibody [N2C2], Internal (TA308950) dilution: 1:1000
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Immunohistochemical analysis of paraffin-embedded OVCA xenograft, using Renin(TA308950) antibody at 1:100 dilution.
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