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Home Antibody All anti-REN antibodies

Anti-REN Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308950
  • Rabbit Polyclonal antibody to Renin (renin)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424660) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for REN (NM_000537)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 70 and 302 of Human REN
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB:1:500-1:3000; IHC:1:100;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens renin (REN)
Alternative NameHNFJ2
Database LinkNP_000528
FunctionRenin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug whole cell lysate) A:293T (anti-REN antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded OVCA xenograft, using Renin(anti-REN antibody) antibody at 1:100 dilution.

 

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