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Home Antibody All anti-PDE4D antibodies

Anti-PDE4D Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308932
  • Rabbit Polyclonal antibody to PDE4D (phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila))
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 746 and 809 of PDE4D (Uniprot ID#Q08499)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.3mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 76kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens phosphodiesterase 4D, cAMP-specific (PDE4D), transcript variant 1
Alternative NameACRDYS2; DPDE3; HSPDE4D; PDE43; PDE4DN2; STRK1
Database LinkNP_001098101
Entrez Gene 5144 Human
FunctionThe PDE4D gene is complex and has at least 9 different isoforms that encode functional proteins. These proteins degrade the second messenger cAMP, which is a key signal transduction molecule in multiple cell types, including vascular cells (Dominiczak and McBride, 2003 [PubMed 14517535]).[supplied by OMIM]
Related PathwayDruggable Genome Purine metabolismProgesterone-mediated oocyte maturation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: A431. B: HeLa. 7.5% SDS PAGE. TA308932 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded H441 xenograft, using PDE4D(TA308932) antibody at 1:100 dilution.
IF Image
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed A431, using PDE4D(TA308932) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:500.

 

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