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Home Antibody All anti-LMNA antibodies

Anti-LMNA Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308920
  • Rabbit Polyclonal antibody to Lamin A/C (lamin A/C)
100ul 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 59 and 259 of Lamin A/C
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB:1:500-1:3000; IHC:1:100;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens lamin A/C (LMNA), transcript variant 3
Alternative NameCDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC;
Database LinkNP_733822
FunctionThe nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq]
Related Pathway
Adipogenesis

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
A: HeLa Nucleus (anti-LMNA antibody diluted at 1:3000
IHC Image
Immunohistochemical analysis of paraffin-embedded H441 Xenograft, using Lamin A/C(anti-LMNA antibody) antibody at 1:100 dilution.

 

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