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Home Antibody All anti-NR3C1 antibodies

Anti-NR3C1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308891
  • Rabbit Polyclonal antibody to Glucocorticoid Receptor beta (nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424874) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IP(1)
IHC(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 265 of Glucocorticoid Receptor beta (Uniprot ID#P04150)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IP Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 82kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 1
Alternative NameGCCR; GCR; GCRST; GR; GRL
Database LinkNP_000167
Entrez Gene 2908 Human
FunctionThe protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. [provided by RefSeq]
Related PathwayNuclear Hormone ReceptorTranscription FactorsDruggable Genome Neuroactive ligand-receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. TA308891 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded Hela xenograft, using Glucocorticoid Receptor beta(TA308891) antibody at 1:500 dilution.
IP Image
Glucocorticoid Receptor beta antibody immunoprecipitates Glucocorticoid Receptor beta protein in IP experiments. IP Sample: 1000 ug HeLa whole cell lysate/extract A. 40 ug HeLa whole cell lysate/extract B. Control with 2.5 ug of preimmune rabbit IgG C. Im

 

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