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Home Antibody All anti-GLDC antibodies

Anti-GLDC Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308885
  • Rabbit Polyclonal antibody to Glycine dehydrogenase (glycine dehydrogenase (decarboxylating))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424873) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 442 and 723 of Glycine dehydrogenase (Uniprot ID#P23378)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Chicken, Rat, Xenopus laevis, Bovine) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (91%), Chicken (85%), Rat (84%), Xenopus laevis (86%), Bovine (92%)

Reference Data

Target NameHomo sapiens glycine dehydrogenase (decarboxylating) (GLDC)
Alternative NameGCE; GCSP; HYGN1
Database LinkNP_000161
Entrez Gene 2731 Human
Entrez Gene 104174 Mouse
Entrez Gene 309312 Rat
FunctionThe enzyme system for cleavage of glycine (glycine cleavage system; GCS; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes; see MIM 238310, MIM 238330, and MIM 238331.[supplied by OMIM]
Related PathwayDruggable Genome Glycine, serine and threonine metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Glycine dehydrogenase antibody detects Glycine dehydrogenase protein by western blot analysis. A. 30 ug HeLa whole cell lysate/extract. B. 30 ug HepG2 whole cell lysate/extract. 5 % SDS-PAGE. Glycine dehydrogenase antibody (TA308885) dilution: 1:500
IHC Image
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using Glycine dehydrogenase(TA308885) antibody at 1:500 dilution.
IF Image
Glycine dehydrogenase antibody [N3C2-2], Internal detects Glycine dehydrogenase protein at mitochondria by immunofluorescent analysis. Sample: HepG2 cells were fixed in ice-cold MeOH for 5 min. Green: Glycine dehydrogenase protein stained by Glycine dehyd

 

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