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Home Antibody All anti-CD44 antibodies

Anti-CD44 Antibody

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SKU Description Amount Price Availability*  
TA308864 Rabbit Polyclonal antibody to CD44 (CD44 molecule (Indian blood group)) 100ul $325 3-7 Days
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WB(2)
IHC(3)
IF(1)

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 258 of CD44
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:20000
Predicted MW Explanation 53kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 5
Alternative NameCDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1
Database LinkNP_001001392
Entrez Gene 960 Human
FunctionThe protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq]
Related PathwayStem cell relevant signaling - DSL/Notch pathwayES Cell Differentiation/IPSTransmembraneAdult stem cellsCancer stem cellsEmbryonic stem cellsDruggable Genome ECM-receptor interactionHematopoietic cell lineage

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

CD44 antibody detects CD44 protein by western blot analysis. A. 30 ug A549 whole cell lysate/extract. B. 30 ug H1299 whole cell lysate/extract. 7.5 % SDS-PAGE. CD44 antibody (TA308864) dilution: 1:5000
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Sample (30 ug of whole cell lysate). A: A549. B: H1299. C: MCF-7. 10% SDS PAGE. TA308864 diluted at 1:10000.
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Immunohistochemical analysis of paraffin-embedded Human pancreatic tumor, using CD44(TA308864) antibody at 1:100 dilution.
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Immunohistochemical analysis of paraffin-embedded Human pancreatic tumor, using CD44(TA308864) antibody at 1:100 dilution.
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Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using CD44 (TA308864) antibody at 1:100 dilution.
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Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using CD44(TA308864) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2000.
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