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Home Antibody All anti-CASP9 antibodies

Anti-CASP9 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308861 Rabbit polyclonal antibody to Caspase-9 (caspase 9, apoptosis-related cysteine peptidase) 100ul $325 3-7 Days
LC409796 CASP9 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for CASP9 (NM_032996)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Assay

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 88 and 416 of Caspase 9 (Uniprot ID#P55211)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Dog, Bovine) Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 46kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Dog (80%), Bovine (82%)

Reference Data

Target NameHomo sapiens caspase 9, apoptosis-related cysteine peptidase (CASP9), transcript variant 3
Alternative NameAPAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56
Database LinkNP_127463
Entrez Gene 842 Human
Entrez Gene 487432 Dog
FunctionThis gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq]
Related PathwayProteaseStem cell - PluripotencyDruggable Genome p53 signaling pathwayApoptosisVEGF signaling pathwayAlzheimer's diseaseParkinson's diseaseAmyotrophic lateral sclerosis (ALS)More Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: 293T. 10% SDS PAGE. TA308861 diluted at 1:1000.


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