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Home Antibody All anti-AGT antibodies

Anti-AGT Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308843 Rabbit Polyclonal antibody to Angiotensinogen (angiotensinogen (serpin peptidase inhibitor, clade A, member 8)) 100ul $325 3-7 Days
LC400005 AGT HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application * Suggested Dilutions
Predicted MW Explanation 53kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT)
Alternative NameANHU; SERPINA8
Database LinkNP_000020
Entrez Gene 183 Human
FunctionThe protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq]
Related PathwaySecreted ProteinDruggable Genome Renin-angiotensin system

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