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Also for NQO1 (NM_001025434)
|Synthetic peptide corresponding to a region within amino acids 213 and 274 of NQO1 (Uniprot ID#P15559)|
|Human (Predicted: Pig, Rhesus Monkey, Bovine, Guinea pig)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Pig (92%), Rhesus Monkey (100%), Bovine (83%), Guinea pig (100%)
|Homo sapiens NAD(P)H dehydrogenase, quinone 1 (NQO1), transcript variant 3|
|DHQU; DIA4; DTD; NMOR1; NMORI; QR1|
Entrez Gene 1728 Human
Entrez Gene 705635 Monkey
|This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Druggable Genome |
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Sample (30 ug of whole cell lysate). A: Molt-4 . B: Raji. 12% SDS PAGE. TA308820 diluted at 1:1000.
NQO1 antibody [C2C3], C-term detects NQO1 protein by Western blot analysis. A. 50 ug mouse heart lysate/extract. 12 % SDS-PAGE. NQO1 antibody [C2C3], C-term (TA308820) dilution: 1:500
NQO1 antibody [C2C3], C-term detects NQO1 protein by Western blot analysis. A. 50 ug rat heart lysate/extract. 12 % SDS-PAGE. NQO1 antibody [C2C3], C-term (TA308820) dilution: 1:500
Immunohistochemical analysis of paraffin-embedded CL1-0 xenograft, using NQO1(TA308820) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NQO1(TA308820) antibody at 1:200 dilution.