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Home Antibody All anti-NQO1 antibodies

Anti-NQO1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308820
  • Rabbit polyclonal antibody to NQO1 (NAD(P)H dehydrogenase, quinone 1)
100ul $325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for NQO1 (NM_001025434)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenSynthetic peptide contain a sequence corresponding to a region within amino acids 213 and 274 of NQO1
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:500-1:3000; IHC:1:500; IF:1:100-1:200;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens NAD(P)H dehydrogenase, quinone 1 (NQO1), transcript variant 3
Alternative NameDHQU; DIA4; DTD; NMOR1; NMORI; QR1
Database LinkNP_001020605
FunctionThis gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Related Pathway

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WB Image
Sample (30 ug of whole cell lysate) A: Molt-4 B: Raji (anti-NQO1 antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded CL1-0 xenograft, using NQO1(anti-NQO1 antibody) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NQO1(anti-NQO1 antibody) antibody at 1:200 dilution.

 

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