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Home Antibody All anti-GAD2 antibodies

Anti-GAD2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308785
  • Rabbit Polyclonal antibody to GAD65 (glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC427399) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for GAD2 (NM_001134366)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide contain a sequence corresponding to a region within amino acids 465 and 528 of Human GAD2
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:1000-1:10000;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (GAD2), transcript variant 2
Alternative NameGAD65
Database LinkNP_001127838
FunctionThis gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq]
Related Pathway

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WB Image
Sample (30 ug of whole cell lysate) A: A431 (anti-GAD2 antibody diluted at 1:1000)

 

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