Home Antibody All anti-MVP antibodies
|Recombinant fragment corresponding to a region within amino acids 158 and 380 of MVP/LRP (Uniprot ID#Q14764)|
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens major vault protein (MVP), transcript variant 2|
Entrez Gene 9961 Human
|This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. [provided by RefSeq]|
|Druggable Genome |
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Sample (30 ug of whole cell lysate). A: Molt-4 . 7.5% SDS PAGE. TA308784 diluted at 1:1000.
MVP/LRP antibody detects MVP protein by Western blot analysis. A. 30 ug Neuro2A whole cell lysate/extract. B. 30 ug GL261 whole cell lysate/extract. C. 30 ug C8D30 whole cell lysate/extract. D. 30 ug BCL-1 whole cell lysate/extract. E. 30 ug Raw264.7 whol
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using LRP(MVP)(TA308784) antibody at 1:500 dilution.
MVP/LRP antibody detects MVP/LRP protein at cytosol on mouse colon by immunohistochemical analysis. Sample: Paraffin-embedded mouse colon. MVP/LRP antibody (TA308784) dilution: 1:500.
Immunofluorescence analysis of paraformaldehyde-fixed A431, using MVP/LRP(TA308784) antibody at 1:200 dilution.