OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-UBE2L3 antibodies

Anti-UBE2L3 Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308758
  • Rabbit Polyclonal antibody to UBE2L3 (ubiquitin-conjugating enzyme E2L 3)
100ul 325 3-7 Days
Add to Shopping Cart
WB(2)
IP(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 92 and 154 of UBE2L3 (Uniprot ID#P68036)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Xenopus laevis, Xenopus Tropicalis, Pig, Chicken, Rhesus Monkey, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF, IP Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 18kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Xenopus laevis (100%), Xenopus Tropicalis (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)

Reference Data

Target NameHomo sapiens ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 2
Alternative NameE2-F1; L-UBC; UBCH7; UbcM4; L-UBC; UBCH7; UbcM4; ubiquitin carrier protein; ubiquitin-conjugating enzyme UBCH7; ubiquitin-protein ligase; ubiquitin-conjugating enzyme E2L 3
Database LinkNP_937800
Entrez Gene 7332 Human
Entrez Gene 699895 Monkey
FunctionThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]
Related Pathway Ubiquitin mediated proteolysisParkinson's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
UBE2L3 antibody detects UBE2L3 protein by Western blot analysis. A. 30 ug Neuro2A whole cell lysate/extract. B. 30 ug GL261 whole cell lysate/extract. C. 30 ug C8D30 whole cell lysate/extract. 15 % SDS-PAGE. UBE2L3 antibody (TA308758) dilution: 1:1000
WB Image
Sample (30 ug of whole cell lysate). A: Hela. B: Hep G2 . 12% SDS PAGE. TA308758 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using UBE2L3(TA308758) antibody at 1:100 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using UBE2L3(TA308758) antibody at 1:200 dilution.
IP Image
Immunoprecipitation of UBE2L3 protein from HeLa whole cell extracts using 5 ug of UBE2L3 antibody (TA308758). Western blot analysis was performed using UBE2L3 antibody (TA308758). An anti-rabbit IgG was used as a secondary reagent.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title