Home Antibody All anti-HMGA2 antibodies
Also for HMGA2 (NM_003484)
|Recombinant fragment corresponding to a region within amino acids 1 and 109 of HMGA2 (Uniprot ID#P52926)|
|Human (Predicted: Pig)
|WB, IHC, IF, IP
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:5000-1:20000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Pig (88%)
|Homo sapiens high mobility group AT-hook 2 (HMGA2), transcript variant 2|
|BABL; HMGI-C; HMGIC; LIPO; STQTL9|
Entrez Gene 8091 Human
|This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
|Druggable Genome |
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Sample (30 ug of whole cell lysate). A: HepG2. B: HCT116. 15% SDS PAGE. TA308757 diluted at 1:10000.
Immunohistochemical analysis of paraffin-embedded H1299 xenograft, using HMGA2(TA308757) antibody at 1:500 dilution.
Immunohistochemical analysis of paraffin-embedded C2C12 xenograft, using HMGA2(TA308757) antibody at 1:500 dilution.
Immunohistochemical analysis of paraffin-embedded RT2 xenograft, using HMGA2(TA308757) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using HMGA2(TA308757) antibody at 1:500 dilution.
Immunoprecipitation of HMGA2 protein from HepG2 nuclear extracts using 5 ug of HMGA2 antibody (TA308757). Western blot analysis was performed using HMGA2 antibody (TA308757). An anti-rabbit IgG was used as a secondary reagent.