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Home Antibody All anti-RAD18 antibodies

Anti-RAD18 Antibody

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SKU Description Amount Price Availability*  
TA308755
  • Rabbit polyclonal antibody to RAD18 (RAD18 homolog (S. cerevisiae))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402768) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for RAD18 (NM_020165)
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 259 of RAD18 (Uniprot ID#Q9NS91)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Bovine) Concentration0.46mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 56kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Bovine (80%)

Reference Data

Target NameHomo sapiens RAD18 E3 ubiquitin protein ligase (RAD18)
Alternative NameRNF73
Database LinkNP_064550
Entrez Gene 56852 Human
FunctionThe protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: Hep G2 . 7.5% SDS PAGE. TA308755 diluted at 1:1000.
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Immunohistochemical analysis of paraffin-embedded Cal27 Xenograft, using RAD18(TA308755) antibody at 1:100 dilution.
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RAD18 antibody [N1C1] detects RAD18 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: RAD18 protein stained by RAD18 antibody [N1C1] (TA308755) diluted at 1:500. Blue: Hoechst 3
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