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Home Antibody All anti-TRIM21 antibodies

Anti-TRIM21 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308743 Rabbit Polyclonal antibody to SSA1 (tripartite motif-containing 21) 100ul $325 In Stock
LC401090 TRIM21 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for TRIM21 (NM_003141)
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 254 and 475 of SSA1 (Uniprot ID#P19474)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Pig, Bovine) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 54kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Pig (81%), Bovine (82%)

Reference Data

Target NameHomo sapiens tripartite motif containing 21 (TRIM21)
Alternative NameRNF81; Ro/SSA; RO52; SSA; SSA1
Database LinkNP_003132
Entrez Gene 6737 Human
FunctionThis gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq]
Related PathwayDruggable Genome Systemic lupus erythematosus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: Molt-4 . 10% SDS PAGE. TA308743 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded DLD-1 xenograft , using SSA1(TA308743) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed A431, using SSA1(TA308743) antibody at 1:200 dilution.


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