Home Antibody All anti-TYK2 antibodies
Also for TYK2 (NM_003331)
|Recombinant fragment corresponding to a region within amino acids 680 and 1187 of TYK2 (Uniprot ID#P29597)|
|Human (Predicted: Mouse, Pig, Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (88%), Pig (88%), Bovine (87%)
|Homo sapiens tyrosine kinase 2 (TYK2)|
Entrez Gene 7297 Human
Entrez Gene 54721 Mouse
|This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq]|
|Protein KinaseDruggable Genome Jak-STAT signaling pathway|
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Sample(30 ug whole cell lysate). A:H1299. B:HeLa S3. 5% SDS PAGE. TA308735 diluted at 1:1000
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TYK2(TA308735) antibody at 1:200 dilution.