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Home Antibody All anti-IDH2 antibodies

Anti-IDH2 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308664 Rabbit Polyclonal antibody to IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial) 100ul $325 2 Weeks
LC400787 IDH2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 56 and 345 of IDH2 (Uniprot ID#P48735)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Rhesus Monkey) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 51kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rhesus Monkey (100%)

Reference Data

Target NameHomo sapiens isocitrate dehydrogenase 2 (NADP+), mitochondrial (IDH2), transcript variant 1
Alternative NameD2HGA2; ICD-M; IDH; IDHM; IDP; IDPM; mNADP-IDH
Database LinkNP_002159
Entrez Gene 3418 Human
Entrez Gene 269951 Mouse
Entrez Gene 701480 Monkey
FunctionIsocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq]
Related Pathway Citrate cycle (TCA cycle)Glutathione metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (50 ug of whole cell lysate). A: Mouse brain. 10% SDS PAGE. TA308664 diluted at 1:1000.

WB Image
Sample(30 ug of whole cell lysate). A:MOLT4. 7.5% SDS PAGE. TA308664 diluted at 1:1000

IHC Image
Immunohistochemical analysis of paraffin-embedded normal gastric epithelium (gland), using IDH2(TA308664) antibody at 1:100 dilution.


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