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Home Antibody All anti-MAPKAPK5 antibodies

Anti-MAPKAPK5 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308640
  • Rabbit polyclonal antibody to PRAK (mitogen-activated protein kinase-activated protein kinase 5)
100ul 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenRecombinant fragment contain a sequence corresponding to a region within amino acids 197 and 457 of PRAK (Uniprot ID#Q8IW41)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Chicken, Pig, Rat, Xenopus tropicalis) Concentration0.62mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 54kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (96%), Chicken (95%), Pig (97%), Rat (96%), Xenopus tropicalis (90%)

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 2
Alternative NameMAPKAP-K5; MK-5; MK5; PRAK
Database LinkNP_620777
Entrez Gene 8550 Human
Entrez Gene 17165 Mouse
Entrez Gene 498183 Rat
FunctionThe protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug of whole cell lysate). A:293T. B:H1299. 7.5% SDS PAGE. TA308640 diluted at 1:500
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PRAK(TA308640) antibody at 1:200 dilution.

 

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