OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-DHH antibodies

Anti-DHH Antibody

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308606 Rabbit polyclonal antibody to Dhh (desert hedgehog homolog (Drosophila)) 100ul $325 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

spacer
WB(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 135 and 396 of Dhh (Uniprot ID#O43323)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat) Concentration0.95mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:5000-1:20000
Predicted MW Explanation 44kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (98%), Rat (98%)

Reference Data

Target NameHomo sapiens desert hedgehog (DHH)
Alternative NameGDXYM; HHG-3; SRXY7
Database LinkNP_066382
Entrez Gene 50846 Human
Entrez Gene 13363 Mouse
Entrez Gene 84380 Rat
FunctionThis gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq]
Related PathwayES Cell Differentiation/IPSProteaseDruggable Genome Hedgehog signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: A431 . 10% SDS PAGE. TA308606 diluted at 1:10000.
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title