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Home Antibody All anti-ITGA2B antibodies

Anti-ITGA2B Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308579
  • Rabbit polyclonal antibody to CD41/Integrin alpha 2b (integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424734) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for ITGA2B (NM_000419)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 210 and 532 of Integrin alpha 2b (Uniprot ID#P08514)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Dog, Bovine) Concentration0.7mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 113kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Dog (88%), Bovine (86%)

Reference Data

Target NameHomo sapiens integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) (ITGA2B)
Alternative NameBDPLT16; BDPLT2; CD41; CD41B; GP2B; GPIIb; GT; GTA; HPA3; PPP1R93
Database LinkNP_000410
Entrez Gene 3674 Human
Entrez Gene 403789 Dog
FunctionITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq]
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Focal adhesionECM-receptor interactionHematopoietic cell lineageRegulation of actin cytoskeletonPathways in cancerSmall cell lung cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: A549. 7.5% SDS PAGE. TA308579 diluted at 1:500.
IHC Image
Immunohistochemical analysis of paraffin-embedded PC13 xenograft, using Integrin alpha 2b(TA308579) antibody at 1:500 dilution.

 

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