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Also for DSG2 (NM_001943)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 176 of Desmoglein-2|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens desmoglein 2 (DSG2)|
|ARVC10; ARVD10; CDHF5; CMD1BB; HDGC|
|Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq]|
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A: 293T B: H1299 C: Molt-4 (anti-DSG2 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded DU145 xenograft , using Desmoglein-2(anti-DSG2 antibody) antibody at 1:100 dilution.