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Home Antibody All anti-RBBP8 antibodies

Anti-RBBP8 Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308515 Rabbit polyclonal antibody to CtIP (retinoblastoma binding protein 8) 100ul $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 452 and 777 of CtIP (Uniprot ID#Q99708)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:1000-1:10000
Predicted MW Explanation 102kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens RB binding protein 8, endonuclease (RBBP8), transcript variant 1
Alternative NameCOM1; CTIP; JWDS; RIM; SAE2; SCKL2
Database LinkNP_002885
Entrez Gene 5932 Human
FunctionThe protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
Sample (30 ug of whole cell lysate). A: Hep G2 . 7.5% SDS PAGE. TA308515 diluted at 1:5000.
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