Home Antibody All anti-EEF2K antibodies
Also for EEF2K (NM_013302)
|Recombinant fragment corresponding to a region within amino acids 1 and 268 of EEF2K (Uniprot ID#O00418)|
|Human, Mouse (Predicted: Bovine)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:10000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Bovine (90%)
|Homo sapiens eukaryotic elongation factor-2 kinase (EEF2K)|
Entrez Gene 29904 Human
Entrez Gene 13631 Mouse
|This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq]|
|Protein KinaseDruggable Genome |
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Sample (50 ug of whole cell lysate). A: mouse liver. 7.5% SDS PAGE. TA308475 diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: A431 . B: H1299. C: Hela. D: Hep G2 . 7.5% SDS PAGE. TA308475 diluted at 1:5000.
Immunohistochemical analysis of paraffin-embedded BT483 xenograft, using eEF-2K(TA308475) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed A431, using eEF-2K(TA308475) antibody at 1:200 dilution.