Home Antibody All anti-RGS10 antibodies
Also for RGS10 (NM_001005339)
|Recombinant fragment corresponding to a region within amino acids 1 and 173 of RGS10 (Uniprot ID#O43665)|
|Human (Predicted: Mouse)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (92%)
|Homo sapiens regulator of G-protein signaling 10 (RGS10), transcript variant 1|
|OTTHUMP00000020597; OTTHUMP00000069158; regulator of G-protein signalling 10; regulator of G-protein signaling 10|
Entrez Gene 6001 Human
Entrez Gene 67865 Mouse
|Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Sample (30 ug of whole cell lysate). A: A431 . 12% SDS PAGE. TA308469 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Breast ca, using RGS10(TA308469) antibody at 1:250 dilution.