Home Antibody All anti-DCK antibodies
|Recombinant fragment corresponding to a region within amino acids 1 and 260 of DCK (Uniprot ID#P27707)|
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:10000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens deoxycytidine kinase (DCK)|
Entrez Gene 1633 Human
Entrez Gene 13178 Mouse
| Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq]|
|Druggable Genome Purine metabolismPyrimidine metabolism|
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Sample (30 ug of whole cell lysate). A: A431. 12% SDS PAGE. TA308454 diluted at 1:5000.
DCK antibody detects DCK protein by western blot analysis. A. 50 ug mouse brain extract. 12 % SDS-PAGE. DCK antibody (TA308454) dilution: 1:1000
DCK antibody detects DCK protein by western blot analysis. A. 30 ug PC-12 whole cell extract. B. 30 ug Rat2 whole cell extract. 12 % SDS-PAGE. DCK antibody (TA308454) dilution: 1:1000
DCK antibody detects DCK protein at cytosol and nucleus on human lung carcinoma by immunohistochemical analysis. Sample: DCK antibody (TA308454) dilution: 1:250.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Deoxycytidine kinase(TA308454) antibody at 1:200 dilution.