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Home Antibody All anti-DCK antibodies

Anti-DCK Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308454 Rabbit Polyclonal antibody to DCK (deoxycytidine kinase) 100ul $325 2 Weeks
LC400272 DCK HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 260 of DCK (Uniprot ID#P27707)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:10000
Predicted MW Explanation 31kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens deoxycytidine kinase (DCK)
Alternative NameMGC117410; MGC138632
Database LinkNP_000779
Entrez Gene 1633 Human
Entrez Gene 13178 Mouse
FunctionDeoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq]
Related PathwayDruggable Genome Purine metabolismPyrimidine metabolism

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: A431. 12% SDS PAGE. TA308454 diluted at 1:5000.

WB Image
DCK antibody detects DCK protein by western blot analysis. A. 50 ug mouse brain extract. 12 % SDS-PAGE. DCK antibody (TA308454) dilution: 1:1000

WB Image
DCK antibody detects DCK protein by western blot analysis. A. 30 ug PC-12 whole cell extract. B. 30 ug Rat2 whole cell extract. 12 % SDS-PAGE. DCK antibody (TA308454) dilution: 1:1000

IHC Image
DCK antibody detects DCK protein at cytosol and nucleus on human lung carcinoma by immunohistochemical analysis. Sample: DCK antibody (TA308454) dilution: 1:250.

IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Deoxycytidine kinase(TA308454) antibody at 1:200 dilution.


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