Home Antibody All anti-RAMP2 antibodies
Also for RAMP2 (NM_005854)
|Synthetic peptide contain a sequence corresponding to a region within amino acids 111 and 175 of Human RAMP2|
||0.5~1.0 mg/ml (Lot Dependent)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens receptor (G protein-coupled) activity modifying protein 2 (RAMP2)|
|The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. [provided by RefSeq]|
Signaling by GPCR
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Sample(30 ug of whole cell lysate) A:MOLT4 B:Raji (anti-RAMP2 antibody diluted at 1:1500
Immunohistochemical analysis of paraffin-embedded SG xenograft, using RAMP2(anti-RAMP2 antibody) antibody at 1:100 dilution.