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Home Antibody All anti-LIG3 antibodies

Anti-LIG3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308391
  • Rabbit polyclonal antibody to DNA ligase 3 (ligase III, DNA, ATP-dependent)
100ul 325 3-7 Days
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IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 765 and 1009 of DNA ligase 3 (Uniprot ID#P49916)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.31mg/ml
Guaranteed Application *IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:
Predicted MW Explanation 113kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens ligase III, DNA, ATP-dependent (LIG3), transcript variant beta
Alternative NameLIG2
Database LinkNP_002302
Entrez Gene 3980 Human
FunctionThis gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Related PathwayDruggable Genome Base excision repair

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Immunohistochemical analysis of paraffin-embedded H441 Xenograft, using DNA ligase 3(TA308391) antibody at 1:100 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A431, using DNA ligase 3(TA308391) antibody at 1:200 dilution.

 

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