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Home Antibody All anti-IL12RB1 antibodies

Anti-IL12RB1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308386
  • Rabbit polyclonal antibody to IL-12R beta1(CD212) (interleukin 12 receptor, beta 1)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC417240) , 20ug
100ul $325 3-7 Days
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Also for IL12RB1 (NM_005535)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 57 and 458 of Human IL12RB1
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens interleukin 12 receptor, beta 1 (IL12RB1), transcript variant 1
Alternative NameCD212; IL-12R-BETA1; IL12RB
Database LinkNP_005526
FunctionThe protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]
Related Pathway
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway

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Sample(30 ug whole cell lysate) A:A431 (anti-IL12RB1 antibody diluted at 1:1000)

 

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