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Home Antibody All anti-CCT2 antibodies

Anti-CCT2 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308346 Rabbit Polyclonal antibody to TCP1 beta (chaperonin containing TCP1, subunit 2 (beta)) 100ul $325 3-7 Days
LC416649 CCT2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(2)
IHC(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 277 and 503 of TCP1 beta (Uniprot ID#P78371)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Pig, Rabbit, Rhesus Monkey, Chimpanzee) Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 58kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Chimpanzee (100%)

Reference Data

Target NameHomo sapiens chaperonin containing TCP1, subunit 2 (beta) (CCT2), transcript variant 1
Alternative Name99D8.1; CCT-beta; CCTB; HEL-S-100n; PRO1633; TCP-1-beta
Database LinkNP_006422
Entrez Gene 10576 Human
Entrez Gene 12461 Mouse
Entrez Gene 717182 Monkey
FunctionThis gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized. [provided by RefSeq]
Related PathwayDruggable Genome

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Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA308346 diluted at 1:1000.
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Sample (30 ug of whole cell lysate). A: Hep G2 . B: Raji. 7.5% SDS PAGE. TA308346 diluted at 1:1000.
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Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using TCP1 beta(TA308346) antibody at 1:100 dilution.
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