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Home Antibody All anti-UNC13D antibodies

Anti-UNC13D Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308332
  • Rabbit Polyclonal antibody to UNC13D (unc-13 homolog D (C. elegans))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403710) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for UNC13D (NM_199242)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 1029 and 1090 of Munc 13-4 (Uniprot ID#Q70J99)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 123kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens unc-13 homolog D (C. elegans) (UNC13D)
Alternative NameFHL3; HLH3; HPLH3; Munc13-4
Database LinkNP_954712
Entrez Gene 201294 Human
FunctionThis gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: Jurkat. B: K562. 5% SDS PAGE. TA308332 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded Stomach, using UNC13D(TA308332) antibody at 1:100 dilution.
IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using Munc 13-4(TA308332) antibody at 1:500 dilution.

 

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