Home Antibody All anti-KLRC1 antibodies
Also for KLRC1 (NM_213658)
|Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of NKG2-A (CD159a)|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens killer cell lectin-like receptor subfamily C, member 1 (KLRC1), transcript variant 3|
|CD159A; NKG2; NKG2A|
|Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq]|
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A: A431 B: HepG2 ( NKG2-A (CD159a) antibody anti-KLRC1 antibody diluted at 1:1000)
Immunofluorescence analysis of methanol-fixed HeLa, using KLRC1(anti-KLRC1 antibody) antibody at 1:200 dilution.