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Home Antibody All anti-CD70 antibodies

Anti-CD70 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308292 Rabbit polyclonal antibody to CD27L (CD27L (CD70)) (CD27L (CD70) molecule) 100ul $325 3-7 Days
LC400501 CD70 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 129 and 193 of CD70 (Uniprot ID#P32970)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Pig) Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 21kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (80%), Rat (80%), Pig (87%)

Reference Data

Target NameHomo sapiens CD70 molecule (CD70)
Alternative NameCD27L; CD27LG; TNFSF7
Database LinkNP_001243
Entrez Gene 970 Human
Entrez Gene 21948 Mouse
Entrez Gene 301132 Rat
FunctionThe protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq]
Related PathwayES Cell Differentiation/IPSTransmembrane Cytokine-cytokine receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: JurKat. 12% SDS PAGE. CD27L (CD70) antibody. TA308292 diluted at 1:1000.
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