Home Antibody All anti-KLRK1 antibodies
Also for KLRK1 (NM_007360)
|Synthetic peptide corresponding to a region within amino acids 86 and 177 of NKG2D|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens killer cell lectin-like receptor subfamily K, member 1 (KLRK1)|
|CD314; D12S2489E; KLR; NKG2-D; NKG2D|
Entrez Gene 22914 Human
|Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. [provided by RefSeq]|
|Transmembrane Natural killer cell mediated cytotoxicity|
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NKG2D antibody [N3C2], Internal detects NKG2D protein at cytosol on human lung carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human lung carcinoma. NKG2D antibody [N3C2], Internal (TA308267) dilution: 1:250.