Home Antibody All anti-RAPGEF5 antibodies
Also for RAPGEF5 (NM_012294)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 179 of Human RAPGEF5|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens Rap guanine nucleotide exchange factor (GEF) 5 (RAPGEF5)|
|GFR; MR-GEF; REPAC|
|Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM]|
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Sample(30 ug of whole cell lysate) A:HeLa S3 (anti-RAPGEF5 antibody diluted at 1:1000)