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Home Antibody All anti-PRKACA antibodies

Anti-PRKACA Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308159
  • Rabbit polyclonal antibody to PRKACA (protein kinase, cAMP-dependent, catalytic, alpha)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419140) , 20ug
100ul 325 3-7 Days
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WB(1)
IF(1)
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Also for PRKACA (NM_002730)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 340 of PRKACA
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB:1:500-1:3000; IF:1:100-1:200;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens protein kinase, cAMP-dependent, catalytic, alpha (PRKACA), transcript variant 1
Alternative NamePKACA
Database LinkNP_002721
FunctioncAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]
Related Pathway
Cell cycle
Hedgehog signaling pathway
MAPK signaling pathway
Melanogenesis
Wnt Signaling Pathway

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WB Image
Sample(30 ug of whole cell lysate) A:HeLa S3 (anti-PRKACA antibody diluted at 1:500)
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PRKACA(anti-PRKACA antibody) antibody at 1:200 dilution.

 

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