OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-RASGRP4 antibodies

Anti-RASGRP4 Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308102
  • Rabbit Polyclonal antibody to RASGRP4 (RAS guanyl releasing protein 4)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC406913) , 20ug
100ul 325 3-7 Days
Add to Shopping Cart
WB(1)
IHC(1)
spacer
Also for RASGRP4 (NM_170604)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenSynthetic peptide contain a sequence corresponding to a region within amino acids 108 and 170 of Human RASGRP4
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB:1:500-1:3000; IHC:1:100;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens RAS guanyl releasing protein 4 (RASGRP4), transcript variant a
Alternative Nameguanyl nucleotide releasing protein 4; RAS guanyl releasing protein 4
Database LinkNP_733749
FunctionThe protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Related Pathway
MAPK signaling pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
A: Jurkat (anti-RASGRP4 antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using RASGRP4 (anti-RASGRP4 antibody) antibody at 1:100 dilution.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title