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Home Antibody All anti-CBS antibodies

Anti-CBS Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308071
  • Rabbit Polyclonal antibody to CBS (cystathionine-beta-synthase)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400017) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IP(1)
IHC(1)
IF(1)
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Also for CBS (NM_000071)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 39 and 251 of CBS (Uniprot ID#P35520)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rabbit, Rat, Bovine, Xenopus tropicalis) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF, IP Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 61kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (94%), Rabbit (95%), Rat (94%), Bovine (94%), Xenopus tropicalis (93%)

Reference Data

Target NameHomo sapiens cystathionine-beta-synthase (CBS), transcript variant 1
Alternative NameHIP4
Database LinkNP_000062
Entrez Gene 875 Human
Entrez Gene 12411 Mouse
Entrez Gene 24250 Rat
FunctionThe protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. [provided by RefSeq]
Related PathwayDruggable Genome Glycine, serine and threonine metabolismCysteine and methionine metabolismSelenoamino acid metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
CBS antibody detects CBS protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract. 7.5 % SDS-PAGE. CBS antibody (TA308071) dilution: 1:1000
IHC Image
Immunohistochemical analysis of paraffin-embedded OVCAR3 xenograft , using CBS(TA308071) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using CBS(TA308071) antibody at 1:200 dilution.
IP Image
CBS antibody immunoprecipitates CBS protein in IP experiments. IP samples: HepG2 whole cell extract. A. 50 ug HepG2 whole cell extract. B. Control with 4 ug of preimmune Rabbit IgG. C. Immunoprecipitation of CBS protein by 4 ug CBS antibody (TA308071). 7.

 

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