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Home Antibody All anti-INPP5B antibodies

Anti-INPP5B Antibody

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SKU Description Amount Price Availability*  
TA308024
  • Rabbit Polyclonal antibody to INPP5B (inositol polyphosphate-5-phosphatase, 75kDa)
100ul $325 3-7 Days

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WB(1)
IHC(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 699 and 949 of INPP5B (Uniprot ID#P32019)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat) Concentration0.34mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 104kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (87%), Rat (87%)

Reference Data

Target NameHomo sapiens inositol polyphosphate-5-phosphatase, 75kDa (INPP5B), transcript variant 1
Alternative Name5PTase
Database LinkNP_005531
Entrez Gene 3633 Human
Entrez Gene 16330 Mouse
Entrez Gene 362590 Rat
FunctionCellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq]
Related PathwayDruggable Genome Inositol phosphate metabolismMetabolic pathwaysPhosphatidylinositol signaling system

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Sample (30 ug of whole cell lysate). A: H1299. 7.5% SDS PAGE. TA308024 diluted at 1:1000.
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Immunohistochemical analysis of paraffin-embedded Ca922 xenograft, using INPP5B(TA308024) antibody at 1:100 dilution.
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