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Home Antibody All anti-RASAL1 antibodies

Anti-RASAL1 Antibody

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SKU Description Amount Price Availability*  
TA308003 Rabbit polyclonal antibody to RASAL1 (RAS protein activator like 1 (GAP1 like)) 100ul $325 2 Weeks
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WB(1)
IF(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 516 and 787 of RASAL1 (Uniprot ID#O95294)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Rat) Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 90kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rat (86%)

Reference Data

Target NameHomo sapiens RAS protein activator like 1 (GAP1 like) (RASAL1), transcript variant 2
Alternative NameRASAL
Database LinkNP_004649
Entrez Gene 8437 Human
Entrez Gene 360814 Rat
FunctionThe protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. TA308003 diluted at 1:1000
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Immunofluorescence analysis of paraformaldehyde-fixed A549, using RASAL1(TA308003) antibody at 1:200 dilution.
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