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Anti-IL12RB2 Antibody

WB(1)

Gene Name Homo sapiens interleukin 12 receptor, beta 2 (IL12RB2), transcript variant 1 Synonyms: RP11-102M16.1 Immunogen Recombinant protein fragment contain a sequence corresponding to a region within amino acids 323 and 665 of Human IL12RB2 Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. Clone Name Isotype IgG Species Reactivity Human Concentration 1mg/ml Purification Purified by antigen-affinity chromatography. (Protein A or G Sepharose) Guaranteed Application * WB Suggested Dilutions WB:1:1000-1:10000; Background The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. [provided by RefSeq] Related Pathway Cytokine-cytokine receptor interaction Jak-STAT signaling pathway

Related Lysate from OriGene • Transient overexpression lysate of interleukin 12 receptor, beta 2 (IL12RB2) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • IL12RB2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • IL12RB2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Il12rb2 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • IL12RB2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Il12rb2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens interleukin 12 receptor, beta 2 (IL12RB2) as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens interleukin 12 receptor, beta 2 (IL12RB2) as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens interleukin 12 receptor, beta 2 (IL12RB2) as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens interleukin 12 receptor, beta 2 (IL12RB2) as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)