Home Antibody All anti-GLE1 antibodies
Also for GLE1 (NM_001003722)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 414 and 656 of GLE1|
||0.5~1.0 mg/ml (Lot Dependent)
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:500; IF:1:100-1:200;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens GLE1 RNA export mediator (GLE1), transcript variant 1|
|GLE1L; hGLE1; LCCS; LCCS1|
|This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate) A: HeLa (anti-GLE1 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft , using GLE1(anti-GLE1 antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using GLE1(anti-GLE1 antibody) antibody at 1:200 dilution.