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Home Antibody All anti-GLE1 antibodies

Anti-GLE1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307943 Rabbit polyclonal antibody to GLE1 (GLE1 RNA export mediator homolog (yeast)) 100ul $325 In Stock
LC423996 GLE1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for GLE1 (NM_001003722)
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OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 414 and 646 of GLE1
Clone Name IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 75kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens GLE1 RNA export mediator (GLE1), transcript variant 1
Alternative NameGLE1L; hGLE1; LCCS; LCCS1
Database LinkNP_001003722
Entrez Gene 2733 Human
FunctionThis gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: HeLa. 7.5% SDS PAGE. TA307943 diluted at 1:1000

IHC Image
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft , using GLE1(TA307943) antibody at 1:500 dilution.

IF Image
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using GLE1(TA307943) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2500.


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