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Anti-OTUB1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307939 Rabbit Polyclonal antibody to OTUB1 (OTU domain, ubiquitin aldehyde binding 1) 100ul $325 3-7 Days
LC402607 OTUB1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for OTUB1 (NM_017670)
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 149 of OTUB1 (Uniprot ID#Q96FW1)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Rat, Pig, Bovine) Concentration0.25mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 31kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rat (100%), Pig (100%), Bovine (100%)

Reference Data

Target NameHomo sapiens OTU deubiquitinase, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1
Alternative NameHSPC263; OTB1; OTU1
Database LinkNP_060140
Entrez Gene 55611 Human
Entrez Gene 107260 Mouse
Entrez Gene 293705 Rat
FunctionThe product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Related PathwayProtease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: Hela. B: Hep G2 . 12% SDS PAGE. TA307939 diluted at 1:1000.

WB Image
Sample (50 ug of whole cell lysate). A: Mouse liver. 12% SDS PAGE. TA307939 diluted at 1:500.

IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using OTUB1(TA307939) antibody at 1:50 dilution.


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