Home Antibody All anti-NANS antibodies
Also for NANS (NM_018946)
|Recombinant fragment corresponding to a region within amino acids 54 and 359 of NANS (Uniprot ID#Q9NR45)|
|Human (Predicted: Mouse, Chicken, Pig, Rat, Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (97%), Chicken (88%), Pig (97%), Rat (97%), Bovine (97%)
|Homo sapiens N-acetylneuraminic acid synthase (NANS)|
Entrez Gene 54187 Human
|This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq]|
| Amino sugar and nucleotide sugar metabolismMetabolic pathways|
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Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. NANS antibody. TA307925 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded normal gastric epithelium (gland), using NANS(TA307925) antibody at 1:100 dilution.