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Home Antibody All anti-NANS antibodies

Anti-NANS Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307925
  • Rabbit polyclonal antibody to NANS (N-acetylneuraminic acid synthase)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC412808) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for NANS (NM_018946)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 54 and 359 of NANS (Uniprot ID#Q9NR45)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Chicken, Pig, Rat, Bovine) Concentration0.21mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 40kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (97%), Chicken (88%), Pig (97%), Rat (97%), Bovine (97%)

Reference Data

Target NameHomo sapiens N-acetylneuraminic acid synthase (NANS)
Alternative NameHEL-S-100; SAS
Database LinkNP_061819
Entrez Gene 54187 Human
Entrez Gene 94181 Mouse
Entrez Gene 298071 Rat
FunctionThis gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq]
Related Pathway Amino sugar and nucleotide sugar metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. NANS antibody. TA307925 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded normal gastric epithelium (gland), using NANS(TA307925) antibody at 1:100 dilution.

 

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