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Home Antibody All anti-SGSH antibodies

Anti-SGSH Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307913 Rabbit polyclonal antibody to SGSH (N-sulfoglucosamine sulfohydrolase) 100ul $325 3-7 Days
LC424866 SGSH HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 318 and 496 of SGSH (Uniprot ID#P51688)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: mouse, Cow, Dog) Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:1000-1:10000
Predicted MW Explanation 57kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: mouse (81%), cow (81%), Dog (82%)

Reference Data

Target NameHomo sapiens N-sulfoglucosamine sulfohydrolase (SGSH)
Alternative NameHSS; MPS3A; SFMD
Database LinkNP_000190
Entrez Gene 6448 Human
Entrez Gene 27029 Mouse
Entrez Gene 403707 Dog
FunctionThis gene encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined. [provided by RefSeq]
Related PathwayDruggable Genome Glycosaminoglycan degradationMetabolic pathwaysLysosome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: Molt-4 . 7.5% SDS PAGE. TA307913 diluted at 1:5000.
Immunohistochemical analysis of paraffin-embedded OVCAR3 xenograft , using SGSH(TA307913) antibody at 1:100 dilution.


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