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Home Antibody All anti-NETO2 antibodies

Anti-NETO2 Antibody EPR3497

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307865
  • Rabbit monoclonal antibody against NETO2(clone EPR3497)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC413317) , 20ug
100ul 325 3-7 Days
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WB(2)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human NETO2 was used as an immunogen.
Clone NameEPR3497 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens neuropilin (NRP) and tolloid (TLL)-like 2 (NETO2), transcript variant 1
Alternative NameBTCL2; NEOT2
Database LinkNP_060562
FunctionNETO2, neuropilin and tolloid-like protein 2, is a transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein receptor class A domain. It also has an intracellular FXNPXY-like motif, which has been shown in other proteins to be essential for the internalization of clathrin coated pits during endocytosis (1). NETO2 is an accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. It increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels (2).
Related Pathway

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WB Image
Western blot - NETO2 antibody [EPR3497]; All lanes : Anti-NETO2 antibody [EPR3497] at 1/1000 dilution.Lane 1 : Human cerebellum lysates.Lane 2 : SH-SY5Y cell lysates.Lane 3 : Human brain lysates.Lysates/proteins at 10 µg per lane.Predicted band size : 60 kDa.
WB Image
Western blot - NETO2 antibody [EPR3497]; All lanes : Anti-NETO2 antibody [EPR3497] at 1/1000 dilution.Lane 1 : mouse brain lysates.Lane 2 : rat brain lysates.Lysates/proteins at 10 µg per lane.Predicted band size : 60 kDa.

 

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