Cdc37 is a cell division cycle control protein of Saccharomyces cerevisiae. It is a molecular chaperone with specific function in cell signal transduction. It has been shown to form a complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. Cdc37 is thought to play a critical role in directing Hsp90 to its target kinases (1)
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